Ticagrelor Inhibits Toll-Like and Protease-Activated Receptor Mediated Platelet Activation in Acute Coronary Syndromes

PURPOSE: Since ticagrelor inhibits the cellular uptake of adenosine, thereby increasing extracellular adenosine concentration and biological activity, we hypothesized that ticagrelor has adenosine-dependent antiplatelet properties. In the current study, we compared the effects of ticagrelor and pras...

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Vydáno v:Cardiovasc Drugs Ther
Hlavní autoři: Wadowski, Patricia P., Weikert, Constantin, Pultar, Joseph, Lee, Silvia, Eichelberger, Beate, Koppensteiner, Renate, Lang, Irene M., Panzer, Simon, Gremmel, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2020
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7093367/
https://ncbi.nlm.nih.gov/pubmed/32062795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10557-019-06932-7
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