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Landscape of BRIP1 molecular lesions in gastrointestinal cancers from published genomic studies

BACKGROUND: BRIP1 is a helicase that partners with BRCA1 in the homologous recombination (HR) step in the repair of DNA inter-strand cross-link lesions. It is a rare cause of hereditary ovarian cancer in patients with no mutations of BRCA1 or BRCA2. The role of the protein in other cancers such as g...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Autor principal: Voutsadakis, Ioannis A
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7093310/
https://ncbi.nlm.nih.gov/pubmed/32231423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v26.i11.1197
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