Development of a System for Post-marketing Population Pharmacokinetic and Pharmacodynamic Studies using Real-World Data from Electronic Health Records

Post-marketing population pharmacokinetic (PK) and pharmacodynamic (PD) studies can be useful to capture patient characteristics affecting PK or PD in real-world settings. These studies require longitudinally measured dose, outcomes, and covariates in large numbers of patients; however, prospective...

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Pubblicato in:Clin Pharmacol Ther
Autori principali: Choi, Leena, Beck, Cole, McNeer, Elizabeth, Weeks, Hannah L., Williams, Michael L., James, Nathan T., Niu, Xinnan, Abou-Khalil, Bassel W., Birdwell, Kelly A., Roden, Dan M., Stein, C. Michael, Bejan, Cosmin A., Denny, Joshua C., Van Driest, Sara L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7093250/
https://ncbi.nlm.nih.gov/pubmed/31957870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1787
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