Small Extracellular Microvesicles Mediated Pathological Communications between Dysfunctional Adipocytes and Cardiomyocytes as a Novel Mechanisms Exacerbating Ischemia/Reperfusion Injury in Diabetic Mice

BACKGROUND: Diabetes exacerbates myocardial ischemia/reperfusion (MI/R) injury by incompletely understood mechanisms. Adipocyte dysfunction contributes to remote organ injury. However, the molecular mechanisms linking dysfunctional adipocytes to increased MI/R injury remain unidentified. The current...

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Publicado no:Circulation
Main Authors: Gan, Lu, Xie, Dina, Liu, Jing, Lau, Wayne Bond, Christopher, Theodore A., Lopez, Bernard, Zhang, Ling, Gao, Erhe, Koch, Walter, Ma, Xin-Liang, Wang, Yajing
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7093230/
https://ncbi.nlm.nih.gov/pubmed/31918577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.119.042640
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