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An abundant quiescent stem cell population in Drosophila Malpighian tubules protects principal cells from kidney stones

Adult Drosophila Malpighian tubules have low rates of cell turnover but are vulnerable to damage caused by stones, like their mammalian counterparts, kidneys. We show that Drosophilarenal stem cells (RSCs) in the ureter and lower tubules comprise a unique, unipotent regenerative compartment. RSCs re...

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Publicat a:eLife
Autors principals: Wang, Chenhui, Spradling, Allan C
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7093152/
https://ncbi.nlm.nih.gov/pubmed/32175841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.54096
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