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Increased Prevalence of TG and TPO Mutations in Sudanese Children With Congenital Hypothyroidism

CONTEXT: Congenital hypothyroidism (CH) is due to dyshormonogenesis in 10% to 15% of subjects worldwide but accounts for 60% of CH cases in the Sudan. OBJECTIVE: To investigate the molecular basis of CH in Sudanese families. DESIGN: Clinical phenotype reporting and serum thyroid hormone measurements...

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Dades bibliogràfiques
Publicat a:J Clin Endocrinol Metab
Autors principals: Bruellman, Ryan J, Watanabe, Yui, Ebrhim, Reham S, Creech, Matthew K, Abdullah, Mohamed A, Dumitrescu, Alexandra M, Refetoff, Samuel, Weiss, Roy E
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7093074/
https://ncbi.nlm.nih.gov/pubmed/31867598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/clinem/dgz297
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