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Silencing of SARS-CoV spike gene by small interfering RNA in HEK 293T cells

Two candidate small interfering RNAs (siRNAs) corresponding to severe acute respiratory syndrome-associated coronavirus (SARS-CoV) spike gene were designed and in vitro transcribed to explore the possibility of silencing SARS-CoV S gene. The plasmid pEGFP-optS, which contains the codon-optimized SAR...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Qin, Zhao-ling, Zhao, Ping, Zhang, Xiao-lian, Yu, Jian-guo, Cao, Ming-mei, Zhao, Lan-juan, Luan, Jie, Qi, Zhong-tian
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Inc. 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7092946/
https://ncbi.nlm.nih.gov/pubmed/15504339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2004.09.180
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