Antibody-mediated synergy and interference in the neutralization of SARS-CoV at an epitope cluster on the spike protein

Incomplete neutralization of virus, especially when it occurs in the presence of excess neutralizing antibody, represents a biological phenomenon that impacts greatly on antibody-mediated immune prophylaxis of viral infection and on successful vaccine design. To understand the mechanism by which a v...

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Bibliographic Details
Published in:Biochem Biophys Res Commun
Main Authors: Zhong, Lilin, Haynes, Lia, Struble, Evi Budo, Tamin, Azaibi, Virata-Theimer, Maria Luisa, Zhang, Pei
Format: Artigo
Language:Inglês
Published: Elsevier 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7092930/
https://ncbi.nlm.nih.gov/pubmed/19861118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.10.115
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