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Ribavirin and interferon-β synergistically inhibit SARS-associated coronavirus replication in animal and human cell lines

Initial in vitro investigations demonstrated type I interferons (IFNs: IFN-α, IFN-β) to inhibit replication of SARS coronavirus (SARS-CoV), but found the nucleoside analogue ribavirin ineffective in Vero cells. In this report, ribavirin was shown to inhibit SARS-CoV replication in five different cel...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Biochem Biophys Res Commun
Päätekijät: Morgenstern, Birgit, Michaelis, Martin, Baer, Patrick C., Doerr, Hans W., Cinatl, Jindrich
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier Inc. 2005
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7092851/
https://ncbi.nlm.nih.gov/pubmed/15607755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2004.11.128
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