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An in vivo cell-based assay for investigating the specific interaction between the SARS-CoV N-protein and its viral RNA packaging sequence

The SARS-CoV nucleocapsid (N) protein serves multiple functions in viral replication, transcription, and assembly of the viral genome complex. Coronaviruses specifically package genomic RNA into assembled virions, and in SARS-CoV, it is reported that this process is driven by an interaction between...

詳細記述

保存先:
書誌詳細
出版年:Biochem Biophys Res Commun
主要な著者: Woo, Jiwon, Lee, Eunice Yoojin, Lee, Mirae, Kim, Taeyeon, Cho, Yong-Eun
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier Inc. 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7092827/
https://ncbi.nlm.nih.gov/pubmed/31594639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2019.09.115
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