Neutrophil Extracellular Traps Induce Human Th17 Cells: Effect of Psoriasis-Associated TRAF3IP2 Genotype

Psoriasis lesions are rich in IL-17-producing T-cells as well as neutrophils, which release webs of DNA-protein complexes known as neutrophil extracellular traps (NETs). Because we and others have observed increased NETosis in psoriatic lesions, we hypothesized that NETs contribute to increased Th17...

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Bibliografische gegevens
Gepubliceerd in:J Invest Dermatol
Hoofdauteurs: Lambert, Sylviane, Hambro, Caely A., Johnston, Andrew, Stuart, Philip E., Tsoi, Lam C, Nair, Rajan P., Elder, James T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7092801/
https://ncbi.nlm.nih.gov/pubmed/30528823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2018.11.021
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