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Transdifferentiation of Muscle Satellite Cells to Adipose Cells Using CRISPR/Cas9-Mediated Targeting of MyoD

Brown adipocytes dissipate energy through non-shivering thermogenesis mediated by UCP1 protein, hence representing a powerful target to overcome obesity due to energy surplus. However, brown adipocytes are scarce in adult humans, especially in obese subjects, urging the development of novel strategi...

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Библиографические подробности
Опубликовано в: :Methods Mol Biol
Главные авторы: Chen, Jingjuan, Wang, Chao, Kuang, Shihuan
Формат: Artigo
Язык:Inglês
Опубликовано: 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7092730/
https://ncbi.nlm.nih.gov/pubmed/30367407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-8897-6_3
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