Local effect of simvastatin combined with different osteoconductive biomaterials and collagen sponge on new bone formation in critical defects in rat calvaria

PURPOSE: To evaluate the local effect of simvastatin (SVT) combined with deproteinized bovine bone (DBB) with hydroxyapatite/β-tricalcium phosphate biphasic ceramics (HA/TCP) and with collagen sponge (CS) on bone repair in critical size defects (CSDs) in rat calvaria. METHODS: Forty-two 5-mm diamete...

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Bibliografiska uppgifter
I publikationen:Acta Cir Bras
Huvudupphovsmän: de Sousa, Dircilei Nascimento, Roriz, Virgílio Moreira, de Oliveira, Guilherme José Pimentel Lopes, Duarte, Wagner Rodrigues, Pinto, Leonardo Nogueira de Miranda Pereira, Vianna, Leonora Maciel de Souza, Carneiro, Fabiana Pirani, Ferreira, Vania Maria Moraes
Materialtyp: Artigo
Språk:Inglês
Publicerad: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2020
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7092666/
https://ncbi.nlm.nih.gov/pubmed/32215463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/s0102-865020200010000002
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