Exosomal MALAT1 sponges miR-26a/26b to promote the invasion and metastasis of colorectal cancer via FUT4 enhanced fucosylation and PI3K/Akt pathway

BACKGROUND: Exosomes are vesicles of endocytic origin released by various cell types and emerging as important mediators in tumor cells. Human metastases-associated lung adenocarcinoma transcript 1 (MALAT1) is a long non-coding RNA known to promote cell proliferation, metastasis, and invasion in col...

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Bibliografiske detaljer
Udgivet i:J Exp Clin Cancer Res
Main Authors: Xu, Jingchao, Xiao, Yang, Liu, Bing, Pan, Shimeng, Liu, Qianqian, Shan, Yujia, Li, Shuangda, Qi, Yu, Huang, Yiran, Jia, Li
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7092616/
https://ncbi.nlm.nih.gov/pubmed/32209115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-020-01562-6
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