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Lack of adverse effects during a target animal safety trial of extended-release buprenorphine in Fischer 344 rats
Extended-release buprenorphine is an effective analgesic in laboratory animals, and its safety has been established in mice but not in rats. The authors used a target animal safety trial to evaluate the safety of extended-release buprenorphine in rats. Fischer 344 rats received post-surgical subcuta...
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Pubblicato in: | Lab Anim (NY) |
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Autori principali: | , , , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
Nature Publishing Group US
2015
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7092016/ https://ncbi.nlm.nih.gov/pubmed/26684956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/laban.745 |
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