PKC promotes proliferation of airway smooth muscle cells by regulating cyclinD1 expression in asthmatic rats

AIM: To determine whether protein kinase C (PKC) has any effect on the expression of cyclinD1, a key regulator of growth control and G(1)/S transition, and to investigate the underlying molecular mechanisms of PKC involving the remodeling of the asthmatic airway smooth muscle (ASM). METHODS: The tre...

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Publicado no:Acta Pharmacol Sin
Main Authors: Qiao, Li-fen, Xu, Yong-jian, Liu, Xian-sheng, Xie, Jun-gang, Wang, Jin, Du, Chun-ling, Zhang, Jian, Ni, Wang, Chen, Shi-xin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7091861/
https://ncbi.nlm.nih.gov/pubmed/18501114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1745-7254.2008.00795.x
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