Coxsackievirus B3 and adenovirus infections of cardiac cells are efficiently inhibited by vector-mediated RNA interference targeting their common receptor

As coxsackievirus B3 (CoxB3) and adenoviruses may cause acute myocarditis and inflammatory cardiomyopathy, isolation of the common coxsackievirus–adenovirus-receptor (CAR) has provided an interesting new target for molecular antiviral therapy. Whereas many viruses show high mutation rates enabling t...

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Publicat a:Gene Ther
Autors principals: Fechner, H, Pinkert, S, Wang, X, Sipo, I, Suckau, L, Kurreck, J, Dörner, A, Sollerbrant, K, Zeichhardt, H, Grunert, H-P, Vetter, R, Schultheiss, H-P, Poller, W
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2007
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7091640/
https://ncbi.nlm.nih.gov/pubmed/17377597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.gt.3302948
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