Intestine-Liver Axis On-Chip Reveals the Intestinal Protective Role on Hepatic Damage by Emulating Ethanol First-Pass Metabolism

Intestine-Liver-on-chip systems can be useful to predict oral drug administration and first-pass metabolism in vitro in order to partly replace the animal model. While organ-on-chip technology can count on sophisticated micro-physiological devices, the engineered organs still remain artificial surro...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: De Gregorio, Vincenza, Telesco, Mariarosaria, Corrado, Brunella, Rosiello, Valerio, Urciuolo, Francesco, Netti, Paolo A., Imparato, Giorgia
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Bioengineering and Biotechnology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7090126/
https://ncbi.nlm.nih.gov/pubmed/32258006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00163
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