CD73 promotes tumor metastasis by modulating RICS/RhoA signaling and EMT in gastric cancer

Tumor microenvironment plays vital roles in shaping cancer diversity, and CD73 (ecto-5′-nucleotidase; NT5E) is an emerging immune checkpoint in modulating cancer progression via conversion of immunostimulatory ATP into immunosuppressive adenosine. However, how the CD73 is regulated and how it functi...

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Udgivet i:Cell Death Dis
Main Authors: Xu, Zhijun, Gu, Chuncai, Yao, Xingxing, Guo, Weihong, Wang, Huanan, Lin, Tian, Li, Fengping, Chen, Da, Wu, Jianhua, Ye, Gengtai, Zhao, Liying, Hu, Yanfeng, Yu, Jiang, Shi, Jiaolong, Li, Guoxin, Liu, Hao
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7089986/
https://ncbi.nlm.nih.gov/pubmed/32205841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2403-6
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