Haplotype-Based Analysis of KIR-Gene Profiles in a South European Population—Distribution of Standard and Variant Haplotypes, and Identification of Novel Recombinant Structures

Inhibitory Killer-cell Immunoglobulin-like Receptors (KIR) specific for HLA class I molecules enable human natural killer cells to monitor altered antigen presentation in pathogen-infected and tumor cells. KIR genes display extensive copy-number variation and allelic polymorphism. They organize in a...

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Vydáno v:Front Immunol
Hlavní autoři: Cisneros, Elisa, Moraru, Manuela, Gómez-Lozano, Natalia, Muntasell, Aura, López-Botet, Miguel, Vilches, Carlos
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7089957/
https://ncbi.nlm.nih.gov/pubmed/32256494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00440
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