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Prolonged-Release (PR) Oxycodone/Naloxone Improves Bowel Function Compared with Oxycodone PR and Provides Effective Analgesia in Chinese Patients with Non-malignant Pain: A Randomized, Double-Blind Trial

INTRODUCTION: Prolonged-release oxycodone/naloxone (OXN PR), combining an opioid analgesic with selective blockade of enteric µ-opioid receptors, provided effective analgesia and improved bowel function in patients with moderate-to-severe pain and opioid-induced constipation in clinical trials predo...

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Detalhes bibliográficos
Publicado no:Adv Ther
Main Authors: Leng, Xiaomei, Zhang, Fengxiao, Yao, Shanglong, Weng, Xisheng, Lu, Kaizhi, Chen, Gouzhong, Huang, Ming, Huang, Yuguang, Zeng, Xiaofeng, Hopp, Michael, Lu, Guodong
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Healthcare 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7089730/
https://ncbi.nlm.nih.gov/pubmed/32020565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12325-020-01244-x
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