Contribution of Leishmania braziliensis antigen-specific CD4(+) T, CD8(+) T, NK and CD3(+)CD56(+)NKT cells in the immunopathogenesis of cutaneous leishmaniasis patients: Cytotoxic, activation and exhaustion profiles

The pathogenesis of cutaneous leishmaniasis (CL) caused by Leishmania (Viannia) braziliensis is dictated mainly by the immune-mediated-tissue inflammation developed. The understanding of the immunological mechanisms that generate tissue damage or resolution of lesions is the key to the development o...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Cunha, Clarissa F., Ferraz-Nogueira, Raquel, Costa, Vanessa F. A., Pimentel, Maria Inês F., Chometon, Thaize Q., Lyra, Marcelo R., Schubach, Armando O., Da-Cruz, Alda Maria, Bertho, Alvaro Luiz
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2020
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7089553/
https://ncbi.nlm.nih.gov/pubmed/32203546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0229400
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