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Analytical Pharmacology: How Numbers Can Guide Drug Discovery
[Image: see text] The unique ways in which pharmacological data compares to mathematical models are described. Examples show that insights into agonist action (prediction of agonism in vivo) and antagonist mechanism of action (orthosteric vs allosteric) can be gained that assist in the candidate sel...
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| Publicado no: | ACS Pharmacol Transl Sci |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American
Chemical Society
2019
|
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7088946/ https://ncbi.nlm.nih.gov/pubmed/32219213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.8b00057 |
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