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A Primary Cell and Organoid Platform for Evaluating Pharmacological Responses in Mammary Epithelial Cells

[Image: see text] An essential process in predicting the in vivo pharmacological activity of a candidate molecule involves the evaluation of target responses using established model systems. While these models largely comprise immortalized cells, which are often serially passaged as monolayers on un...

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Bibliografiske detaljer
Udgivet i:ACS Pharmacol Transl Sci
Main Authors: Stewart, Teneale A., Davis, Felicity M.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2020
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7088941/
https://ncbi.nlm.nih.gov/pubmed/32259089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.9b00090
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