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Time-series analysis in imatinib-resistant chronic myeloid leukemia K562-cells under different drug treatments

Chronic myeloid leukemia (CML) is characterized by the accumulation of active BCR-ABL protein. Imatinib is the first-line treatment of CML; however, many patients are resistant to this drug. In this study, we aimed to compare the differences in expression patterns and functions of time-series genes...

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Bibliografiske detaljer
Udgivet i:J Huazhong Univ Sci Technolog Med Sci
Main Authors: Zhao, Yan-hong, Zhang, Xue-fang, Zhao, Yan-qiu, Bai, Fan, Qin, Fan, Sun, Jing, Dong, Ying
Format: Artigo
Sprog:Inglês
Udgivet: Huazhong University of Science and Technology 2017
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7088819/
https://ncbi.nlm.nih.gov/pubmed/28786057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11596-017-1781-1
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