Aldosterone-induced kidney injury is mediated by NFκB activation

BACKGROUND: Aldosterone induces inflammation and fibrosis in the kidney, while nuclear factor κB (NFκB) plays key roles in inflammation mediated by various cytokines. Here, we determined the roles of NFκB activation in aldosterone-induced kidney injury. METHODS: We used unilaterally nephrectomized r...

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Bibliografiske detaljer
Udgivet i:Clin Exp Nephrol
Main Authors: Fukuda, Seiichi, Horimai, Chihiro, Harada, Kaori, Wakamatsu, Toshifumi, Fukasawa, Hiroshi, Muto, Susumu, Itai, Akiko, Hayashi, Matsuhiko
Format: Artigo
Sprog:Inglês
Udgivet: Springer Japan 2010
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7087855/
https://ncbi.nlm.nih.gov/pubmed/21072674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10157-010-0373-1
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