Acyclic analogs of nucleosides. Synthesis and in vitro antiviral activity of hydroxyalkyl-2-(trifluoromethylthiomethyl) benzimidazoles

In a search for novel antiviral compounds of the ‘doubly modified’ nucleoside type, we have prepared 1-(4-hydroxy-2-oxabutyl)-, 1-(4-hydroxy-3-hydroxymethyl-2-oxabutyl)-, 1-(4-hydroxy-1-hydroxymethy1-2-oxabutyl)-, 1-(4-hydroxy-1-methyl-2-oxabutyl), 1-(4,5-dihydroxy-2-oxapentyl)-, 1-(5-hydroxy-2-oxap...

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Publicado no:Chem Heterocycl Compd (N Y)
Main Authors: Yavorskii, A. é., Turov, A. V., Gogoman, I. V., Sobko, A. I., Tatskaya, V. N., Kvachev, V. G., Florent'ev, V. L.
Formato: Artigo
Idioma:Inglês
Publicado em: Kluwer Academic Publishers-Plenum Publishers 1989
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7087781/
https://ncbi.nlm.nih.gov/pubmed/32214415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/BF00480754
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