Nintedanib Inhibits Wnt3a-Induced Myofibroblast Activation by Suppressing the Src/β-Catenin Pathway

Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease characterized by epithelial cell damage, myofibroblast activation, and collagen deposition. Multiple studies have documented that the Wnt/β-catenin pathway is aberrantly activated in IPF and plays a vital role in myofibroblast diffe...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Li, Xiaohe, Liu, Xiaowei, Deng, Ruxia, Gao, Shaoyan, Yu, Haiyan, Huang, Kai, Jiang, Qiuyan, Liu, Rui, Li, Xiaoping, Zhang, Liang, Zhou, Honggang, Yang, Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7087487/
https://ncbi.nlm.nih.gov/pubmed/32231574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00310
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