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Obstacles to detecting isoforms using full-length scRNA-seq data

BACKGROUND: Early single-cell RNA-seq (scRNA-seq) studies suggested that it was unusual to see more than one isoform being produced from a gene in a single cell, even when multiple isoforms were detected in matched bulk RNA-seq samples. However, these studies generally did not consider the impact of...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Genome Biol
Päätekijät: Westoby, Jennifer, Artemov, Pavel, Hemberg, Martin, Ferguson-Smith, Anne
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7087381/
https://ncbi.nlm.nih.gov/pubmed/32293520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-01981-w
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