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Beta-cyclodextrin derivatives as carriers to enhance the antiviral activity of an antisense oligonucleotide directed toward a coronavirus intergenic consensus sequence

The ability of cyclodextrins to enhance the antiviral activity of a phosphodiester oligodeoxynucleotide has been investigated. Aff18-mer oligodeoxynucleotide complementary to the initiation region of the mRNA coding for the spike protein and containing the intergenic consensus sequence of an enteric...

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Bibliographic Details
Published in:Arch Virol
Main Authors: Abdou, S., Collomb, J., Sallas, F., Marsura, A., Finance, C.
Format: Artigo
Language:Inglês
Published: Springer-Verlag 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7087074/
https://ncbi.nlm.nih.gov/pubmed/9672621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s007050050182
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