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Porcine reproductive and respiratory syndrome virus nucleocapsid protein modulates interferon-β production by inhibiting IRF3 activation in immortalized porcine alveolar macrophages

Porcine reproductive and respiratory syndrome virus (PRRSV) infection appears to elicit a weak innate immune response suppressing type 1 interferon (IFN) production. Recent studies have revealed that several nonstructural proteins encoded by the PRRSV genome independently antagonize the type 1 IFN s...

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Detalhes bibliográficos
Publicado no:Arch Virol
Main Authors: Sagong, Mingeun, Lee, Changhee
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Vienna 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7086947/
https://ncbi.nlm.nih.gov/pubmed/21947566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00705-011-1116-7
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