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Targeted inhibition of immunodeficiency virus replication in lymphocytes through retroviral mediated gene transfer

To test the feasibility of gene therapy for AIDS patients, an animal model is needed to evaluate the efficacy and safety of this approach. Antiviral genes (encoding antisense RNA or viral protein) derived from Simian immunodeficiency virus (SIV) were efficiently targeted into CD4+ lymphocytes throug...

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Detalles Bibliográficos
Publicado en:Arch Virol
Autores principales: Tung, F. Y. -T., Daniel, M. D.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer-Verlag 1993
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7086800/
https://ncbi.nlm.nih.gov/pubmed/7504917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/BF01313779
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