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A time-of–drug addition approach to target identification of antiviral compounds

Insight into the mode of action of newly discovered antiviral agents is now almost a prerequisite for clinical development. This protocol describes a method that provides information on the target of inhibitors of the human immunodeficiency virus (HIV); it can also be adapted to other viruses. The r...

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Dettagli Bibliografici
Pubblicato in:Nat Protoc
Autori principali: Daelemans, Dirk, Pauwels, Rudi, De Clercq, Erik, Pannecouque, Christophe
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7086561/
https://ncbi.nlm.nih.gov/pubmed/21637207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2011.330
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