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Downregulation of PD-L1 via amide analogues of brefelamide: Alternatives to antibody-based cancer immunotherapy

The therapeutic blockade of immune checkpoint has emerged as an effective treatment option for a broad range of tumors. However, the objective tumor response is still limited to a small number of cases and tumor types. The full utility of monoclonal antibody (mAb)-based treatment is hindered by seve...

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Bibliografiske detaljer
Udgivet i:Exp Ther Med
Main Authors: Zhang, Jing, Yamada, Osamu, Kida, Shinya, Murase, Shinya, Hattori, Toshio, Oshima, Yoshiteru, Kikuchi, Haruhisa
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7086297/
https://ncbi.nlm.nih.gov/pubmed/32256803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2020.8553
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