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Styrene maleic-acid lipid particles (SMALPs) into detergent or amphipols: An exchange protocol for membrane protein characterisation

Membrane proteins are traditionally extracted and purified in detergent for biochemical and structural characterisation. This process is often costly and laborious, and the stripping away of potentially stabilising lipids from the membrane protein of interest can have detrimental effects on protein...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta Biomembr
Main Authors: Hesketh, Sophie J., Klebl, David P., Higgins, Anna J., Thomsen, Maren, Pickles, Isabelle B., Sobott, Frank, Sivaprasadarao, Asipu, Postis, Vincent L.G., Muench, Stephen P.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7086155/
https://ncbi.nlm.nih.gov/pubmed/31945320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2020.183192
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