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Putting the brakes on a myosin motor

Insulin-stimulated trafficking of GLUT4 requires the myosin motor Myo1C and signaling adaptor 14-3-3β. Originally, it was thought that 14-3-3β promotes GLUT4 transport by binding the Myo1C lever arm and activating the Myo1C motor. New work by Ji and Ostap using in vitro assays reveals that 14-3-3β b...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Eddington, Casey, Titus, Margaret A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7086042/
https://ncbi.nlm.nih.gov/pubmed/32198186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.H120.013153
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