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Extrahepatic deficiency of transferrin receptor 2 is associated with increased erythropoiesis independent of iron overload
Transferrin receptor 2 (TFR2) is a transmembrane protein expressed mainly in hepatocytes and in developing erythroid cells and is an important focal point in systemic iron regulation. Loss of TFR2 function results in a rare form of the iron-overload disease hereditary hemochromatosis. Although TFR2...
Guardat en:
| Publicat a: | J Biol Chem |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7086028/ https://ncbi.nlm.nih.gov/pubmed/32054685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010535 |
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