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Succinate Supplement Elicited “Pseudohypoxia” Condition to Promote Proliferation, Migration, and Osteogenesis of Periodontal Ligament Cells

Most mesenchymal stem cells reside in a niche of low oxygen tension. Iron-chelating agents such as CoCl(2) and deferoxamine have been utilized to mimic hypoxia and promote cell growth. The purpose of the present study was to explore whether a supplement of succinate, a natural metabolite of the tric...

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Опубликовано в: :Stem Cells Int
Главные авторы: Mao, Huimin, Yang, Andi, Zhao, Yunhe, Lei, Lang, Li, Houxuan
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7085835/
https://ncbi.nlm.nih.gov/pubmed/32215014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/2016809
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