Interleukin-22 ameliorates acute-on-chronic liver failure by reprogramming of impaired regeneration pathways in mice

BACKGROUND & AIMS: Acute-on-chronic liver failure (ACLF) is a clinical syndrome defined by liver failure on preexisting chronic liver disease and is often associated with bacterial infection with high short-term mortality. Experimental models that fully reproduce ACLF and effective pharmacologic...

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Veröffentlicht in:J Hepatol
Hauptverfasser: Xiang, Xiaogang, Feng, Dechun, Hwang, Seonghwan, Ren, Tianyi, Wang, Xiaolin, Trojnar, Eszter, Matyas, Csaba, Mo, Ruidong, Shang, Dabao, He, Yong, Seo, Wonhyo, Shah, Vijay H., Pacher, Pal, Xie, Qing, Gao, Bin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7085428/
https://ncbi.nlm.nih.gov/pubmed/31786256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2019.11.013
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