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Dual SGLT1/SGLT2 Inhibitor Phlorizin Ameliorates Non-Alcoholic Fatty Liver Disease and Hepatic Glucose Production in Type 2 Diabetic Mice

PURPOSE: NAFLD is a hepatic component of type 2 diabetes mellitus (T2D), in which impaired hepatic glucose production plays an important role. Inhibitors of sodium glucose transporter 2 (SGLT2) reduce glycemia and exert beneficial effects on diabetic complications. Recently, dual SGLT1/2 inhibition...

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Detalhes bibliográficos
Publicado no:Diabetes Metab Syndr Obes
Main Authors: David-Silva, Aline, Esteves, João Victor, Morais, Mychel Raony P T, Freitas, Helayne Soares, Zorn, Telma Maria, Correa-Giannella, Maria Lucia, Machado, Ubiratan Fabres
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7085338/
https://ncbi.nlm.nih.gov/pubmed/32231437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DMSO.S242282
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