General toxicity assessment of the novel aldose reductase inhibitor cemtirestat

Cemtirestat, 3-mercapto-5H-[1,2,4]-triazino[5,6-b] indole-5-acetic acid was recently designed and patented as a highly selective and efficient aldose reductase inhibitor endowed with antioxidant activity. The aim of the present study was to assess the general toxicity of cemtirestat using in silico...

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Опубликовано в: :Interdiscip Toxicol
Главные авторы: PRNOVÁ, Marta ŠOLTÉSOVÁ, RAČKOVÁ, Lucia, KOVÁČIKOVÁ, Lucia, BALLEKOVÁ, Jana, VISKUPIČOVÁ, Jana, MICHÁLIKOVÁ, Silvia, TAŞKOPARAN, Betul, ELMAZOĞLU, Zübeyir, RIŽNER, Tea LANIŠNIK, KARASU, Cimen, BANERJEE, Sreeparna, ŠTEFEK, Milan
Формат: Artigo
Язык:Inglês
Опубликовано: Slovak Toxicology Society SETOX 2019
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7085302/
https://ncbi.nlm.nih.gov/pubmed/32210700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2478/intox-2019-0014
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