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The Role of CHK1 Varies with the Status of Oestrogen-receptor and Progesterone-receptor in the Targeted Therapy for Breast Cancer

Objective: The therapeutic effects of the checkpoint kinase 1 (CHK1)-targeted inhibition in tumor therapy have been confirmed, but how to choose an effective application method in breast cancer with heterogeneous molecular characteristics has remained unclear. Methods: We evaluated the status of CHK...

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Détails bibliographiques
Publié dans:Int J Biol Sci
Auteurs principaux: Xu, Wei, Huang, Minghua, Guo, Jia, Zhang, Huiting, Wang, Depeng, Liu, Tiantian, Liu, Haiting, Chen, Shiming, Gao, Peng, Mu, Kun
Format: Artigo
Langue:Inglês
Publié: Ivyspring International Publisher 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7085233/
https://ncbi.nlm.nih.gov/pubmed/32210727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.41627
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