Hsp90 Relieves Heat Stress-Induced Damage in Mouse Kidneys: Involvement of Antiapoptotic PKM2-AKT and Autophagic HIF-1α Signaling

Heat stress can particularly affect the kidney because of its high rate of adenosine triphosphate consumption. Competition between apoptosis and autophagy-mediated survival always exists in damaged tissue. And Hsp90 can enhance cellular protection to resist heat stress. However, the relationship bet...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Chen, Bixia, Yang, Bo, Zhu, Jie, Wu, Jiaxin, Sha, Junzhou, Sun, Jiarui, Bao, Endong, Zhang, Xiaohui
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7084842/
https://ncbi.nlm.nih.gov/pubmed/32121259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21051646
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