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What Are the Molecular Mechanisms by Which Functional Bacterial Amyloids Influence Amyloid Beta Deposition and Neuroinflammation in Neurodegenerative Disorders?

Despite the enormous literature documenting the importance of amyloid beta (Aβ) protein in Alzheimer’s disease, we do not know how Aβ aggregation is initiated and why it has its unique distribution in the brain. In vivo and in vitro evidence has been developed to suggest that functional microbial am...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Friedland, Robert P., McMillan, Joseph D., Kurlawala, Zimple
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7084682/
https://ncbi.nlm.nih.gov/pubmed/32121263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21051652
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