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The SNP rs2298383 Reduces ADORA2A Gene Transcription and Positively Associates with Cytokine Production by Peripheral Blood Mononuclear Cells in Patients with Multiple Chemical Sensitivity

Systemic inflammation and immune activation are striking features of multiple chemical sensitivity (MCS). The rs2298383 SNP of ADORA2A gene, coding for adenosine receptor type 2A (A2AR), has been involved in aberrant immune activation. Here we aimed to assess the prevalence of this SNP in 279 MCS pa...

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Bibliografische gegevens
Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Cannata, Attilio, De Luca, Chiara, Korkina, Liudmila G., Ferlazzo, Nadia, Ientile, Riccardo, Currò, Monica, Andolina, Giulia, Caccamo, Daniela
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7084623/
https://ncbi.nlm.nih.gov/pubmed/32182774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21051858
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