The SNP rs2298383 Reduces ADORA2A Gene Transcription and Positively Associates with Cytokine Production by Peripheral Blood Mononuclear Cells in Patients with Multiple Chemical Sensitivity

Systemic inflammation and immune activation are striking features of multiple chemical sensitivity (MCS). The rs2298383 SNP of ADORA2A gene, coding for adenosine receptor type 2A (A2AR), has been involved in aberrant immune activation. Here we aimed to assess the prevalence of this SNP in 279 MCS pa...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Cannata, Attilio, De Luca, Chiara, Korkina, Liudmila G., Ferlazzo, Nadia, Ientile, Riccardo, Currò, Monica, Andolina, Giulia, Caccamo, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7084623/
https://ncbi.nlm.nih.gov/pubmed/32182774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21051858
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