The Fate of Th17 Cells is Shaped by Epigenetic Modifications and Remodeled by the Tumor Microenvironment

Th17 cells represent a subset of CD4+ T cells characterized by the master transcription factor RORγt and the production of IL-17. Epigenetic modifications such as post-translational histone modifications and DNA methylation play a key role in Th17 cell differentiation and high plasticity. Th17 cells...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Renaude, Elodie, Kroemer, Marie, Loyon, Romain, Binda, Delphine, Borg, Christophe, Guittaut, Michaël, Hervouet, Eric, Peixoto, Paul
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7084267/
https://ncbi.nlm.nih.gov/pubmed/32121394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21051673
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