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The Serum Concentration of Anti-Aging Proteins, Sirtuin1 and αKlotho in Patients with End-Stage Kidney Disease on Maintenance Hemodialysis

INTRODUCTION: Sirtuin1 (SIRT1) acts as an anti-aging protein due to anti-apoptotic, anti-oxidative and anti-inflammatory effect and is implicated in several diseases including diabetes or cardiovascular problems. SIRT1 renal overexpression indicates oxidative stress. Similarly, αKlotho was primarily...

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Detalhes bibliográficos
Publicado no:Clin Interv Aging
Main Authors: Zbroch, Edyta, Bazyluk, Angelika, Malyszko, Jolanta, Koc-Zorawska, Ewa, Rydzewska-Rosolowska, Alicja, Kakareko, Katarzyna, Hryszko, Tomasz
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7084123/
https://ncbi.nlm.nih.gov/pubmed/32214805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CIA.S236980
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