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Metabolic and genetic basis for auxotrophies in Gram-negative species

Auxotrophies constrain the interactions of bacteria with their environment, but are often difficult to identify. Here, we develop an algorithm (AuxoFind) using genome-scale metabolic reconstruction to predict auxotrophies and apply it to a series of available genome sequences of over 1,300 Gram-nega...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Seif, Yara, Choudhary, Kumari Sonal, Hefner, Ying, Anand, Amitesh, Yang, Laurence, Palsson, Bernhard O.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7084086/
https://ncbi.nlm.nih.gov/pubmed/32132208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1910499117
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