A carregar...

Nf1 deletion results in depletion of the Lhx6 transcription factor and a specific loss of parvalbumin(+) cortical interneurons

Neurofibromatosis 1 (NF1) is caused by mutations in the NF1 gene, which encodes the protein, neurofibromin, an inhibitor of Ras activity. Cortical GABAergic interneurons (CINs) are implicated in NF1 pathology, but the cellular and molecular changes to CINs are unknown. We deleted mouse Nf1 from the...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Angara, Kartik, Pai, Emily Ling-Lin, Bilinovich, Stephanie M., Stafford, April M., Nguyen, Julie T., Li, Katie X., Paul, Anirban, Rubenstein, John L., Vogt, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7084085/
https://ncbi.nlm.nih.gov/pubmed/32123116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1915458117
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!