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Cervical carcinoma risk associate with genetic polymorphisms of NEIL2 gene in Chinese population and its significance as predictive biomarker

Genetic polymorphisms of NEIL1 and NEIL2 maybe change protein function, and increased carcinogenesis. In this study, seven NEIL1 SNPs and three NEIL2 SNPs were selected. 400 CSCCs, 400 CIN III, and 1200 normal healthy controls were genotyped by mismatch amplification PCR. mRNA and protein expression...

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Ye, Feng, Liu, Jia, Wang, Hanzhi, Chen, Xiaojing, Cheng, Qi, Chen, Huaizeng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7083954/
https://ncbi.nlm.nih.gov/pubmed/32198476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-62040-9
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