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Cervical carcinoma risk associate with genetic polymorphisms of NEIL2 gene in Chinese population and its significance as predictive biomarker

Genetic polymorphisms of NEIL1 and NEIL2 maybe change protein function, and increased carcinogenesis. In this study, seven NEIL1 SNPs and three NEIL2 SNPs were selected. 400 CSCCs, 400 CIN III, and 1200 normal healthy controls were genotyped by mismatch amplification PCR. mRNA and protein expression...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Ye, Feng, Liu, Jia, Wang, Hanzhi, Chen, Xiaojing, Cheng, Qi, Chen, Huaizeng
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7083954/
https://ncbi.nlm.nih.gov/pubmed/32198476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-62040-9
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